Pimenova, T., Nazabal, A., Roschitzki, B., Seebacher, J., Rinner, O., Zenobi, R. Epitope mapping on bovine prion protein using chemical cross-linking and mass spectrometry. J. Massspectrometry 2008, 43, 183-195.
Pimenova 2008  (800 kb)

Laffont-Proust, I., Haessig, R., Haïk, S., Simon, S., Grassi, J., Fonta, C., Faucheux, B.A., Moya, K.L. Truncated PrPc in mammalian brain: interspecies variation and location in membrane rafts. Biol Chem. 2006, 387(3), 297-300.
Laffont-Proust 2006  (150 kb)

Mishra, S., Saleh, A., Espino, P.S., Davie, J.R., Murphy L.J. Phosphorylation of Histones by Tissue Transglutaminase. . Biol. Chem., Vol. 2006, 281 (9), 5532-5538.

Mishra, S., Murphy, L.J. Tissue Transglutaminase Has Intrinsic Kinase Activity. J. Biol. Chem 2004, 279 (23), 23863-23868.
Mishra 2004  (300 kb)

Grochola, L.-P., Greither, T., Taubert, H.W., Moeller, P., Knippschild, U., Udelnow, A., Henne-Bruns, D., Wuerl, P. Prognostic Relevance of hTERT mRNA Expression in Ductal Adenocarcinoma of the Pancreas. Neoplasia. 2008; 10: 973–976..
Grochola 2008  (250 kb)

Stahlberg, A.; Kubista, M.; Pfaffl, M. Comparison of reverse transcriptases in gene expression analysis. Clin.Chem. 2004; 50: 1678-1680.
Stahlberg 2004  (152 kb)

Rodel, C.; Haas, J.; Groth, A.; Grabenbauer, G.G.; Sauer, R.; Rodel, F. Spontaneous and radiation-induced apoptosis in colorectal carcinoma cells with different intrinsic radiosensitivities: survivin as a radioresistance factor. Int. J. Radiat. Oncol. Biol. Phys. 2003 ; 55 : 1341-1347.
Rodel 2003  (152 kb)

Smith, S.; Vigilant, L.; Morin, P.A. The effects of sequence length and oligonucleotide mismatches on 5' exonuclease assay efficiency. Nucleic.Acids.Res. 2002; 30: e111.
Smith 2002  (441 kb)

Lind K, Norbeck J. Immuno-qPCR detection of the tandem affinity purification (TAP)-tag as a sensitive and accurate tool suitable for large-scale protein quantification. Proteomics 2007; 24: 4414-4423.
Lind 2007  (360 kb)

Taubert, H., Bartel, F., Greither, T., Bache, M., Kappler, M., Koehler, T., Boehnke, A., Lautenschlaeger, C., Schmidt, H., Holzhausen, H.-J., Hauptmann, S., Wuerl, P. Association of HDM2-transcript levels with age of onset and prognosis in soft tissue sarcomas. Mol. Cancer Res. 2008 (in press)

Philipp, W.J., Groth, D., Giles, K., Vodrazka, P., Schimmel, H., Feysagguet, M., Toomik, R., Schacher, P., Osman, A.A., Lachmann, I., Wear, A., Arsac, J.N., Prusiner, S.B. Transgenic mouse brains for the evaluation and quality control of BSE tests. Biol. Chem. 2007; 388(3), 349-54.
Philipp 2007  (200 kb)

Edelmann, A., Rost, A.-K., Köhler, T. A new real-time PCR detection method. BIOforum 6/2006, p. 57.
Edelmann 2006  (200 kb)

Gofflot, S., Deprez, M., Moualij, B., Osman, A.A., Thonnart, J.F., Hougrand, O., Heinen, E. and Zorzi, W. Immunoquantitative PCR for Prion Protein Detection in Sporadic Creutzfeldt-Jakob Disease. Clinical Chemistry 2005; 51, 1605-1611.
Gofflot 2005  (900 kb)

Kahlenberg F, Lachmann I, Tschiedel S, Schneider-Mergener J, Osman AA, Sack U, Mothes T. Reactivity of mouse gliadin antibodies with deamidated gliadin. In "From Proteomics to Molecular Epidemiology: Relevance of Autoantibodies" edited by Conrad K et al., Report on the 6th Dresden Symposium on Autoantibodies held in Dresden on September 4-7, 2005.
Kahlenberg 2005  (370 kb)

Taubert H., Kappler M., Bache M., Bartel F., Köhler T., Lautenschläger C., Blümke K., Würl P., Schmidt H., Meye A., Hauptmann S. Elevated expression of survivin-splice variants predicts a poor outcome for soft-tissue sarcomas patients. Oncogene 2005; 24, 5258-5261.

Lange, T.; Bumm, T.; Otto, S.; Al-Ali, H.-K.; Krug, D.; Köhler, T.; Niederwieser, D.; Krahl, R.; Deininger, M.W.N. Quantitative reverse transcription polymerase chain reaction should not replace conventional cytogenetics for monitoring patients with chronic myeloid leukemia during the early phase of imatinib therapy. Haematologica 2004; 89: 49-57.
Hematologica 2004  (777 kb)

Henterich N, Osman A A, Mendez E, Mothes T. Assay of gliadin by real-time immunopolymerase chain reaction. Nahrung 2003; 47:345-348
Fuessel, S.; Sickert, D.; Meye, A.; Klenk, U.; Schmidt, U.; Schmitz, M.; Rost, A.K.; Weigle, B.; Kiessling, A.; Wirth, M.P. Multiple tumor marker analyses (PSA, hK2, PSCA, trp-p8) in primary prostate cancers using quantitative RT-PCR. Int. J. Oncol. 2003; 23: 121-128.
Lange T, Guenther C, Koehler T, Krahl R, Musiol S, Leiblein S, Al-Ali HK, Van Hoomissen I, Niederwieser D, Deininger MW. High levels of BAX, low levels of MRP-1 and high platelets are independent predictors of response to imatinib in myeloid blast crisis of CML. Blood 2003; 101: 2152-2155.
Lange et al Blood 2003  (30 kb)

Osman A.A., Richter T., Stern M., Conrad K., Henker J., Brandsch C., Zimmer K.P., Mothes T.. Production of recombinant human tissue transglutaminase using the baculovirus expression system, and its application for serological diagnosis of coeliac disease. Eur J Gastroenterol Hepatol. 2002; 14:1217-1223
Osman 2002  (247 kb)

Stembera K., Buchynskyy A., Vogel S., Knoll D., Osman A.A., Ayala J. A., Welzel P. Moenomycin-mediated affinity purification of penicillin-binding protein 1b. Chembiochem. 2002; 3: 332-340.
Lachmann I., Droessler K. Inhibition of hemolytic activity of Aeromonas salmonicida GCAT in rainbow trout red blood cells by a monoclonal antibody. DAO 2002; 51:81-83.
Kahlenberg F., Lachmann I., Tschiedel S., Schneider-Mergener J., Osman A.A., Sack U., Mothes T. Reactivity of mouse gliadin antibodies with deamidated gliadin. In "From Proteomics to Molecular Epidemiology: Relevance of Autoantibodies” edited by Conrad K et al., Report on the 6th Dresden Symposium on Autoantibodies held in Dresden on September 4-7, 2002
T. Köhler, C. Schill, M.W. Deininger, R. Krahl, S. Borchert, D. Hasenclever, S. Leiblein, O. Wagner, D. Niederwieser. High bad and bax mRNA expression negative outcome in acute myeloid leukemia (AML). Leukemia 2002, 16: 22-29.
Leukemia 2002  (170 kb)

P. Würl, M. Kappler, A. Meye, F. Bartel, T. Köhler, C. Lautenschläger, M. Bache, H. Schmidt, H. Taubert. Co-expression of survivin and TERT: risk of tumour-related death in patients with soft-tissue sarcoma. Lancet 2002; 359: 943-945.
Lancet 2002  (437 kb)

T. Köhler, P. Würl, A. Meye, C. Lautenschläger, F. Bartel, S. Borchert, M. Bache, H. Schmidt, H.-J. Holzhausen, H. Taubert. High bad and bcl-xL gene expression and combined bad, bcl-xL, bax and bcl-2 mRNA levels: Molecular predictors for survival of stage 2 soft tissue sarcoma patients. Anticancer Res. 2002, 22: 1553-1560.

Amin M., Uhlig H. H., Kamprad M., Karbe J., Osman A. A., Grahmann F, Hummelsheim F, Mothes T. Neurological Disease-Associated Autoantibodies against an Unknown Protein Encoded by a RES4-22 Homologous Gene. Scand J Immunol. 2001; 53:204-208.
Amin 2001  (161 kb)

Gore M. A., Brandes F., Kaup F. J., Lenzner R., Mothes T., Osman A. A. Callitrichid nutrition and food sensitivity. J. Med. Primatol. 2001; 30:179-184.
Osman A. A., Uhlig H. H., Valdes I., Amin M., Mendez E., Mothes T. Monoclonal antibody recognizing a potential coeliac toxic repetitive pentapeptide epitope in gliadins. Eur. J. Gastroenterol. Hepatol. 2001; 13:1189-1193.
Osman 2001  (202 kb)

M. Kappler, T. Köhler, P. Distelkötter, M. Schmitz, F. Bartel, P. Würl, P. Rieber, H. Schmidt, M. Bache, H. Taubert, A. Meye. Increased survivin transcript levels - a negative predictor of survival in soft tissue sarcoma patients. Int. J. Cancer (Pred. Oncol) 2001; 95: 360-363.
International Journal of Cancer 2001  (678 kb)

M.W. Deininger, S.A. Vieira, Y. Parada, L. Banerji, E.W. Lam, G. Peters, F.X. Mahon, T. Köhler, J.M. Goldman, Melo JV. Direct Relation between BCR-ABL Tyrosine Kinase Activity and Cyclin D2 Expression in Lymphoblasts. Cancer Res 2001; 61: 8005-8013.
Cancer Research 2001  (480 kb)

Lachmann I, Sann H, Kamprad M. Detection of anti-calpain autoantibodies in sera of patients with symptoms of autoimmune diseases. Immunobiology 2001; 204 (1-2): 217.

H. H. Uhlig, J. Lichtenfeld, A. A. Osman, T. Richter, T. Mothes. Evidence for existence of coeliac disease autoantigens apart from tissue transglutaminase. Eur. J. Gastroentero. Hepatol. 2000; 12: 1017-1020.
Uhlig 2000  (359 kb)

Osman A. A., Günnel T., Dietl A., Uhlig H. H., Amin M., Fleckenstein B., Richter T., Mothes T. B-Cell Epitopes of Gliadin. Clin. Exp. Immunol. 2000; 121: 248-254.
Osman 2000  (112 kb)

Hofmann J, Gerstenberger S, Lachmann I, Atreya CD, Liebert UG. Rubella virus nonstructural protein 2 is a minor immunogen.Virus Res. 2000; 68: 155-160.
H. Taubert; T. Koehler; A. Meye; F. Bartel, C. Lautenschläger; S. Borchert; M. Bache; H. Schmidt; P. Würl. mdm2 gene expression level is a prognostic factor in soft tissue sarcoma. Mol Med 2000; 6: 50-59.

Köhler T., A.-K. Rost, K. Purschwitz, S. Vondran, H. Remke, O. Wagner, V. Richter. Genotyping of human apolipoprotein E alleles by the new quantitative, microplate based CASSI-detection assay. In: Polymorphism Detection & Analysis (Burczak JD, Mardis E, eds.), 2000, chapter 39, pp. 397-407. ISBN 1-881299-47-3

C. Schroeder, A. A. Osman, D. Roggenbuck, Th. Mothes. IgA-Gliadin antibodies, IgA-containing circulating immune complexes, and IgA glomerular deposits in marmoset wasting syndrome. Nephrol. Dial. Transplant. 1999; 14: 1875-1880.
Schroeder 1999  (239 kb)

T. Köhler, S. Leiblein, S. Borchert, J. Eller, A.-K. Rost, D. Laßner, R. Krahl, W. Helbig, O. Wagner, H. Remke. Absolute levels of mdr-1, MRP, and bcl-2 mRNA and tumor remission in acute leukemia. Adv. Exp. Med. Biol. 1999; 457:177-185.
Th. Köhler, D. Lerche, A. Meye, Ch. Weisbrich, O. Wagner. Automated analysis of nucleic acids by quantitative PCR using DNA coated ready-to-use reaction tubes. J. Lab. Med. 1999; 23: 408-414.
Köhler, T. Competitor Calibration and Analysis of Competitive Amplified PCR Products by High-Performance Liquid Chromatography (HPLC). In: Kochanowski, B and Reischl, U. (eds.), Quantitative PCR Protocols, Methods in Molecular Biology, Chapter 9, pp. 147-156, Humana Press Inc., Totowa, NY, 1999. (ISBN 0-89603-518-2)

A. A. Osman, H. Uhlig, B. Thamm, J. Schneider-Mergener, Th. Mothes. Use of phage display technique for detection of epitopes recognized by polyclonal rabbit gliadin antibodies. FEBS Lett. 1998; 433:103-107
Osman 1998  (99 kb)

H. Uhlig, A. A. Osman, I. Tanev I, J. Viehweg, T. Mothes. Role of tissue transglutaminase in gliadin binding to reticular extracellular matrix and relation to coeliac disease autoantibodies. Autoimmunity 28:185-195 (1998)
Lachmann I, Wagner U, Haedge D, Droessler K. Generation and preliminary characterization of monoclonal antibodies directed to glycerophospholipid:cholesterol acyltransferase (GCAT) native epitopes of Aeromonas salmonicida. Dis. Aquat. Organ. 1998; 33:73-75.
T. Köhler, J. Eller, S. Leiblein, D. Laßner, W. Helbig, H. Remke, O. Wagner. Mechanisms responsible for therapy resistance of acute myelogenous leukemia (AML). Int. J. Pharmacol. Ther. 1998; 36: 97-98.
T. Köhler, A.-K. Rost, K. Purschwitz, S. Vondran, H. Remke, O. Wagner, V. Richter. Genotyping of Human Apolipoprotein E Alleles by the New Quantitative, Microplate Based CASSI-Detection Assay. Biotechniques 1998; 25: 80-85.

U. Bendix, S. Lentz, M. Rothschild, I. Lehmann, A. A. Osman, Th. Mothes. Effect of ?-interferon on binding of gliadin and other food peptides to the human intestinal cell line HT-29. Clin. Chim. Acta 1997; 261: 69-80.
Bendix 1997  (776 kb)

G. Birkenmeier, A. A. Osman, G. Kopperschläger, Th. Mothes. Epitope mapping by screening of phage display libraries of a monoclonal antibody directed against the receptor binding domain of human ß2-macroglobulin. FEBS Lett. 1997; 416:193-196.
Birkenmeier 1997  (525 kb)

Köhler T., Rost A.-K., Remke H. Calibration and storage of DNA competitors used for contamination-protected competitive PCR. Biotechniques 1997; 23: 722-726.
Aust, G., Hofmann, A., Laue, S., Rost, A., Köhler, T., Scherbaum, W.A. Human thyroid carcinoma cell lines and normal thyrocytes: expression and regulation of matrix metalloproteinase-1 and tissue matrix metalloproteinase inhibitor-1 messenger-RNA and protein. Thyroid 1997, 7: 713-724.
Köhler, T., D. Laßner, A.-K. Rost, S. Leiblein and H. Remke. Polymerase chain reaction related approaches to quantitate absolute levels of mRNA coding for the multidrug resistance-associated protein and P-glycoprotein. In: Pieters, R., G.J.L. Kaspers and A.J.P. Veerman (Eds.). Drug resistance in leukemia and lymphoma II, Advances in Blood Disorders series, Harwood Academic Publishers, London 1997, p 265-273.

G. Bolte, A. Osman, Th. Mothes, M. Stern. Peptic-tryptic digests of gliadin: contaminating proteases interfere with gastrointestinal binding characteristics. Clin. Chim. Acta 1996; 247: 59-70
Bolte 1996  (906 kb)

A. A. Osman, Th. Richter, M. Stern, Th. Mothes. The IgA subclass distribution of endomysium and gliadin antibodies in human sera is different. Clin. Chim. Acta 1996; 255: 145 – 152.
H. Börner, A. A. Osman, Th. Meergans, T. Weiske, Th. Mothes. Isolation of antigens recognised by coeliac disease autoantibodies and their use in enzyme immunoassay of endomysium and reticulin antibody positive human sera. Clin. Exp. Immunol. 1996; 106: 344 – 350.
Börner 1996  (758 kb)

T. Köhler, D. Laßner, A.-K. Rost, B. Thamm, B. Pustowoit and H. Remke (Eds.), Quantitation of mRNA by polymerase chain reaction - Nonradioactive PCR methods, Springer-Verlag, Heidelberg, 1995.